Raptors G Kyle Lowry (back) to miss first matchup against former teammate DeMar DeRozan

Kyle Lowry will not be on the floor Thursday.

The 27-year-old guard will miss the Raptors’ matchup with the Spurs in San Antonio because of a back injury, coach Nick Nurse told reporters pregame. Lowry has not played since Dec. 22 and has been out for eight of Toronto’s last nine games.

The matchup Thursday would have been the first time Lowry faced former Raptors teammate DeMar DeRozan since he was traded to the Spurs in exchange for Kawhi Leonard and Danny Green this summer. The pair played together in Toronto from 2012-18 and are close friends.

Lowry is averaging 14.4 points and a career-high 9.8 assists in 34.1 minutes per game this season. He’s shooting 43.3 percent from the field and 32.5 percent from 3-point range.

Nurse said last weekend he was “a little bit worried” about Lowry, who received pain-relieving and anti-inflammatory injections in his back Tuesday.

“You’re always concerned,” Nurse said Sunday, via ESPN. “You want an All-Star player back as soon as possible. Any of our guys, we want them back as soon as possible … I think we’re positive and hopeful that it’s going in the right direction, and we’ll see him back soon.”

The Raptors have been one of the best teams in the NBA this season and will enter their game against the Spurs with a 28-11 record.